Reflections are being made on the actual benefits, future possibilities and challenges for the use of the Internet in health interventions as a result of the initiatives at the highest level being developed in the field of e-health in Spain. Thus, analysis is required of the models, methodologies and specific aspects involved in their introduction, an analysis that has to stress the specific nature of virtual interventions, as opposed to face-to-face interventions, and the areas for these interventions and the disorders that can be dealt with virtually. The advantages of interventions on the Internet are also highlighted: accessibility, keeping to treatments, lower costs, anonymity and flexibility. In turn and in contrast to these advantages of interventions on the Internet, the requirements are also listed: the team that plans and designs the intervention has to be multidisciplinary, the healthcare professional has to offer high levels of empathy, and the intervention has to be aimed specifically at the user in question, taking into account that the profile of an online user differs from that of a face-to-face user. Finally, the prospects for the future are assessed and the essential aspects that need to form part of interventions on the Internet set out.